About: radioisotope iodine-131?
a radioactive isotope of iodine is used in both the diagnosis and treatment of a condition of the thyroid gland.
this gland naturally takes up standard iodine as part of its function.
if a patient has an overactive thyroid it concentrates too much iodine contained by the gland and this has serious effects on the patient's heatlh.
how might the radioisotope iodine-131 be used to:
a) identify an overactive thyroid gland
b) treat the overactive thyroid
i have absolutely no belief for either question..
iodine-131 emits beta! beta particle cannot penetrate a lot! how would they detect the rays from outside? i thought only gamma beam emitting particles can be used as tracers?!
and how would you use this radioactive particle to treat the thyroid?
Answers:
A) Iodine-131 can be detected by an MRI. Concentration contained by the thyroid at abnormally high concentrations would indicate a thyroid problem.
B) Given at lose doses, iodine-131 can be used as a chemotherapeutic towards thyroid cancers. It'll bring back concentrated in cancerous cells and beta-emission will inevitably destroy the cell.
I131 is no longer used to diagnose overactive thyroid glands. T3 and Free T4 levels are used for measurement of thyroid flurry. These are blood tests performed on venous blood samples. I131 is used as treatment to treat hyperthyroidism and goiter. A high dose of about 150 millicuries is given orally which is taken up by the thyroid gland. The gland is ablated by the beta radiation. The dignified levels of gamma radiation also emitted is the reason these patients are isolated during treatment and next told to stay away from young children for about 6 weeks. I123, a short lived pure gamma emitter, is currently used to diagnose thyroid tumors. The normal constituent of the gland takes up I123 while most solid tumors do not and will be seen as cold areas on the scan images. I131 is used to evaluate for residual tumor after thyroid resection and to look for metastatic thyroid tumors.
small doses serve identify the problem, larger doses mean larger doses of radiation to the hot spots that had shown up on the initial scan.
I-131 is both an Beta and Gamma emitter, there is also a I-123 which is mostly a gamma emitter, and have a shorter half life (13 hours as compared to 8 days) so it might be better for scanning.
Beta's controlled range allow for localized tissue distruction to the thyroid while the gamma emissions are for detection.
Here is additional setting:
http://www.merck.com/mmpe/sec12/ch152/ch… Source(s): Goodman and Gilman's Pharmacological Basis of Therapeutics, 11th edition, pages 1533 to 1535.
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this gland naturally takes up standard iodine as part of its function.
if a patient has an overactive thyroid it concentrates too much iodine contained by the gland and this has serious effects on the patient's heatlh.
how might the radioisotope iodine-131 be used to:
a) identify an overactive thyroid gland
b) treat the overactive thyroid
i have absolutely no belief for either question..
iodine-131 emits beta! beta particle cannot penetrate a lot! how would they detect the rays from outside? i thought only gamma beam emitting particles can be used as tracers?!
and how would you use this radioactive particle to treat the thyroid?
Answers:
A) Iodine-131 can be detected by an MRI. Concentration contained by the thyroid at abnormally high concentrations would indicate a thyroid problem.
B) Given at lose doses, iodine-131 can be used as a chemotherapeutic towards thyroid cancers. It'll bring back concentrated in cancerous cells and beta-emission will inevitably destroy the cell.
I131 is no longer used to diagnose overactive thyroid glands. T3 and Free T4 levels are used for measurement of thyroid flurry. These are blood tests performed on venous blood samples. I131 is used as treatment to treat hyperthyroidism and goiter. A high dose of about 150 millicuries is given orally which is taken up by the thyroid gland. The gland is ablated by the beta radiation. The dignified levels of gamma radiation also emitted is the reason these patients are isolated during treatment and next told to stay away from young children for about 6 weeks. I123, a short lived pure gamma emitter, is currently used to diagnose thyroid tumors. The normal constituent of the gland takes up I123 while most solid tumors do not and will be seen as cold areas on the scan images. I131 is used to evaluate for residual tumor after thyroid resection and to look for metastatic thyroid tumors.
small doses serve identify the problem, larger doses mean larger doses of radiation to the hot spots that had shown up on the initial scan.
I-131 is both an Beta and Gamma emitter, there is also a I-123 which is mostly a gamma emitter, and have a shorter half life (13 hours as compared to 8 days) so it might be better for scanning.
Beta's controlled range allow for localized tissue distruction to the thyroid while the gamma emissions are for detection.
Here is additional setting:
http://www.merck.com/mmpe/sec12/ch152/ch… Source(s): Goodman and Gilman's Pharmacological Basis of Therapeutics, 11th edition, pages 1533 to 1535.
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