Function of tamoxifen?

I have a MCQ and i narrowed to down to these two but i don't know which is correct. Please help

Tamoxifen is an anticancer drug that bind the estrogen receptor and

A. Blocks estrogen receptor dimerisation
B. Acts as an antagonist to limit tumour growth
Answers:
Tamoxifen competitively binds to estrogen receptors on tumors and other tissue target, producing a nuclear complex that decreases DNA synthesis and inhibits estrogen effects. Tamoxifen is cytostatic rather than cytocidal, it prevents the cancerous cells from dividing thereby limiting tumor growth.

Your answer is B Source(s): Pharmacist

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