Can you appropriate an NSAID within liver disease?
like cirrhosis? Im thinking no but my professor said its fine.
Answers:
As a general rule, yes. There are increased risks, especially with advanced cirrhosis. These folks tend to hold esophageal varices from portal hypertension, and they'll occasionally bleed like you wouldn't believe. They also tend to have elevated prothrombin times (the protein's made in the liver), making it slightly more potential they'll bleed. NSAID's, of course, decrease platelet aggregation, another risk for bleeding unrelated to the others.
Yes, you can thieve NSAIDs with liver diseases but you have to be more careful. Certain NSAIDs, specifically ibuprofen, are known to cause hepatitis on their own, but typically with large doses and long-term use. So, they are ok to use...but you just have to be more careful.
The big piece to watch out for with NSAID use is kidney disease, all NSAIDs are adept of causing kidney failure/degradation. Source(s): pharmacy student
referenced clinical pharmacology text book and a few websites (lexicomp, etc) just to be sure
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Answers:
As a general rule, yes. There are increased risks, especially with advanced cirrhosis. These folks tend to hold esophageal varices from portal hypertension, and they'll occasionally bleed like you wouldn't believe. They also tend to have elevated prothrombin times (the protein's made in the liver), making it slightly more potential they'll bleed. NSAID's, of course, decrease platelet aggregation, another risk for bleeding unrelated to the others.
Yes, you can thieve NSAIDs with liver diseases but you have to be more careful. Certain NSAIDs, specifically ibuprofen, are known to cause hepatitis on their own, but typically with large doses and long-term use. So, they are ok to use...but you just have to be more careful.
The big piece to watch out for with NSAID use is kidney disease, all NSAIDs are adept of causing kidney failure/degradation. Source(s): pharmacy student
referenced clinical pharmacology text book and a few websites (lexicomp, etc) just to be sure
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