If Im taking Nardil, which over the counter cold drug is safe and sound to pocket?
Im congested throughout my nasal passages and sinus' as well as having body ache and a sore throat. Wondering which over the counter meds are safe to use with MAOIs. Im just looking for warning on this and will consult my doctor first before taking anything. Thank you!
Answers:
I don't think there is one. I took Mucinex when I had a cold and used plain salin nasal spray. Talk to the pharmacist beforehand you buy anything.
basically most of the OTC cold meds, variations of tylenol, and nyquil/ dayquil have interactions near nardil
Interactions
Selected Sympathomimetics/MAOI's
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
MONOGRAPH TITLE: Selected Sympathomimetics/MAOI's
SEVERITY LEVEL: 1-Contraindicated Drug Combination: This drug combination is contraindicated and generally should not be dispensed or administered to one and the same patient.
MECHANISM OF ACTION: Catecholamine stores increased by MAOIs can be released by indirect acting sympathomimetics such as ephedrine and amphetamine. MAO inhibitors also interfere with gut and liver metabolism of direct acting sympathomimetics (eg oral phenylephrine).
CLINICAL EFFECTS: Concurrent use of MAOIs may result in potentiation of sympathomimetic effects, which may result contained by headaches, hypertensive crisis, toxic neurological effects, and malignant hyperpyrexia. Fatalities have occurred.
PREDISPOSING FACTORS: None determined.
PATIENT MANAGEMENT: Concurrent use of monoamine oxidase inhibitors and sympathomimetics is contraindicated.
DISCUSSION: Indirect acting sympathomimetic amines may result in abrupt elevation of blood pressure when administered to patients taking monoamine oxidase inhibitors, resulting in a potentially fatal hypertensive crisis.
Mixed (direct and indirect) acting sympathomimetics enjoy also been shown to interact with monoamine oxidase inhibitors depending on their degree of indirect bustle. The direct-acting sympathomimetics have not been reported to interact. Dopamine is metabolized by monoamine oxidase, and its pressor effect is enhanced by monoamine oxidase inhibitors.
Since procarbazine, an antineoplastic agent, is a weak monoamine oxidase inhibitor, hypertensive reaction may result from its concurrent use with indirect and mixed acting sympathomimetics.
Furazolidone, an antibacterial with monoamine oxidase inhibitor action, have also been shown to interact with indirect acting sympathomimetics.
Linezolid is another antibacterial with monoamine oxidase inhibitor properties.
Foods containing colossal amounts of tyramine have also been implicated in this interaction.
Selected Narcotics/MAOIs
This information is generalized and not intended as specific medical guidance. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
MONOGRAPH TITLE: Selected Narcotics/MAOIs
SEVERITY LEVEL: 1-Contraindicated Drug Combination: This drug combination is contraindicated and generally should not be dispensed or administered to the same merciful.
MECHANISM OF ACTION: Unknown.
CLINICAL EFFECTS: The concurrent use of some narcotics with MAOIs has resulted in hypotension, hyperpyrexia, sedation, somnolence, and disappearance.
PREDISPOSING FACTORS: None determined.
PATIENT MANAGEMENT: Dextromethorphan, diamorphine, meperidine, methadone, and morphine should not be used in patients taking MAOIs.
Two US manufacturers of morphine states that morphine should not be used within 14 days of a MAOI.
Three UK manufacturer of morphine state that concurrent use with MAOIs is contraindicated.
The Australian manufacturer of methadone states that methadone should not be administered to patients receiving MAOIs. The US businessman of methadone states that if concurrent use is warranted, a sensitivity test using repeated small, incremental doses of methadone with assiduous monitoring of the patient's condition and vital signs should be performed.
DISCUSSION: The interaction between meperidine and MAOIs has be well documented. There are two reports of potential interactions between MAOIs and dextromethorphan. In another case report, the concurrent use of propoxyphene and phenylzine resulted in sedation and somnolence. The merciful had previously taken both agents alone with no adverse effects.
Although some studies have shown that morphine does not interact next to MAOIs, other data indicates that MAOIs markedly potentiates the effect of morphine.
One study indicates that methadone does not interact with MAOIs; however, the UK manufacturer of methadone states that concurrent use is contraindicated. US manufacturer recommend sensitivity tests with small, incremental doses of methadone in patients maintain on MAOIs with careful observation of necessary signs.
There is one case report of serotonin syndrome with concurrent meperidine and linezolid.
Furazolidone and linezolid are known to be monoamine oxidase inhibitors.
Selected Antihistamines/MAOIs
This information is generalized and not intended as specific medical warning. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
MONOGRAPH TITLE: Selected Antihistamines/MAOIs
SEVERITY LEVEL: 1-Contraindicated Drug Combination: This drug combination is contraindicated and generally should not be dispensed or administered to the same merciful.
MECHANISM OF ACTION: MAOIs prolong and intensify the effects of antihistamines.(1-4)
CLINICAL EFFECTS: Concurrent use of antihistamines and a MAOI may result in severe hypotension.(1-4)
PREDISPOSING FACTORS: None determined.
PATIENT MANAGEMENT: Concurrent use of antihistamines and a MAOI is contraindicated.(1-4)
DISCUSSION: MAOI's may prolong and intensify the effects of antihistamines, resulting in severe hypotension.(1-4) In a case report, a forgiving, upon concurrent administration with linezolid and diphenhydramine, developed acute onset hyperactive delirium beside aggression, paranoia, and vivid auditory and visual hallucinations. Once diphenhydramine was discontinued, adjectives symptoms resided.(5)
Another case report describes a patient having cyproheptadine added to their phenelzine analysis in an attempt to relieve the patients anorgasmia. The patient began to suddenly experience ocular hallucination after taking the cyproheptadine for two months. Once the medication was terminated, the hallucinations stopped occurring in 48 hours Source(s): Medscape.com drug interaction checker
For the congestion you can use saline nasal spray as often as needed. A cool-mist humidifier will help beside the sore throat, as will sucking on hard candies. Tylenol or Advil would be fine for the body aches. Do not use Excedrin, as the caffeine in Excedrin is contraindicated while using MAOIs. Source(s): PharmD nominee
Call a pharmacist...
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Answers:
I don't think there is one. I took Mucinex when I had a cold and used plain salin nasal spray. Talk to the pharmacist beforehand you buy anything.
basically most of the OTC cold meds, variations of tylenol, and nyquil/ dayquil have interactions near nardil
Interactions
Selected Sympathomimetics/MAOI's
This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
MONOGRAPH TITLE: Selected Sympathomimetics/MAOI's
SEVERITY LEVEL: 1-Contraindicated Drug Combination: This drug combination is contraindicated and generally should not be dispensed or administered to one and the same patient.
MECHANISM OF ACTION: Catecholamine stores increased by MAOIs can be released by indirect acting sympathomimetics such as ephedrine and amphetamine. MAO inhibitors also interfere with gut and liver metabolism of direct acting sympathomimetics (eg oral phenylephrine).
CLINICAL EFFECTS: Concurrent use of MAOIs may result in potentiation of sympathomimetic effects, which may result contained by headaches, hypertensive crisis, toxic neurological effects, and malignant hyperpyrexia. Fatalities have occurred.
PREDISPOSING FACTORS: None determined.
PATIENT MANAGEMENT: Concurrent use of monoamine oxidase inhibitors and sympathomimetics is contraindicated.
DISCUSSION: Indirect acting sympathomimetic amines may result in abrupt elevation of blood pressure when administered to patients taking monoamine oxidase inhibitors, resulting in a potentially fatal hypertensive crisis.
Mixed (direct and indirect) acting sympathomimetics enjoy also been shown to interact with monoamine oxidase inhibitors depending on their degree of indirect bustle. The direct-acting sympathomimetics have not been reported to interact. Dopamine is metabolized by monoamine oxidase, and its pressor effect is enhanced by monoamine oxidase inhibitors.
Since procarbazine, an antineoplastic agent, is a weak monoamine oxidase inhibitor, hypertensive reaction may result from its concurrent use with indirect and mixed acting sympathomimetics.
Furazolidone, an antibacterial with monoamine oxidase inhibitor action, have also been shown to interact with indirect acting sympathomimetics.
Linezolid is another antibacterial with monoamine oxidase inhibitor properties.
Foods containing colossal amounts of tyramine have also been implicated in this interaction.
Selected Narcotics/MAOIs
This information is generalized and not intended as specific medical guidance. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
MONOGRAPH TITLE: Selected Narcotics/MAOIs
SEVERITY LEVEL: 1-Contraindicated Drug Combination: This drug combination is contraindicated and generally should not be dispensed or administered to the same merciful.
MECHANISM OF ACTION: Unknown.
CLINICAL EFFECTS: The concurrent use of some narcotics with MAOIs has resulted in hypotension, hyperpyrexia, sedation, somnolence, and disappearance.
PREDISPOSING FACTORS: None determined.
PATIENT MANAGEMENT: Dextromethorphan, diamorphine, meperidine, methadone, and morphine should not be used in patients taking MAOIs.
Two US manufacturers of morphine states that morphine should not be used within 14 days of a MAOI.
Three UK manufacturer of morphine state that concurrent use with MAOIs is contraindicated.
The Australian manufacturer of methadone states that methadone should not be administered to patients receiving MAOIs. The US businessman of methadone states that if concurrent use is warranted, a sensitivity test using repeated small, incremental doses of methadone with assiduous monitoring of the patient's condition and vital signs should be performed.
DISCUSSION: The interaction between meperidine and MAOIs has be well documented. There are two reports of potential interactions between MAOIs and dextromethorphan. In another case report, the concurrent use of propoxyphene and phenylzine resulted in sedation and somnolence. The merciful had previously taken both agents alone with no adverse effects.
Although some studies have shown that morphine does not interact next to MAOIs, other data indicates that MAOIs markedly potentiates the effect of morphine.
One study indicates that methadone does not interact with MAOIs; however, the UK manufacturer of methadone states that concurrent use is contraindicated. US manufacturer recommend sensitivity tests with small, incremental doses of methadone in patients maintain on MAOIs with careful observation of necessary signs.
There is one case report of serotonin syndrome with concurrent meperidine and linezolid.
Furazolidone and linezolid are known to be monoamine oxidase inhibitors.
Selected Antihistamines/MAOIs
This information is generalized and not intended as specific medical warning. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment.
MONOGRAPH TITLE: Selected Antihistamines/MAOIs
SEVERITY LEVEL: 1-Contraindicated Drug Combination: This drug combination is contraindicated and generally should not be dispensed or administered to the same merciful.
MECHANISM OF ACTION: MAOIs prolong and intensify the effects of antihistamines.(1-4)
CLINICAL EFFECTS: Concurrent use of antihistamines and a MAOI may result in severe hypotension.(1-4)
PREDISPOSING FACTORS: None determined.
PATIENT MANAGEMENT: Concurrent use of antihistamines and a MAOI is contraindicated.(1-4)
DISCUSSION: MAOI's may prolong and intensify the effects of antihistamines, resulting in severe hypotension.(1-4) In a case report, a forgiving, upon concurrent administration with linezolid and diphenhydramine, developed acute onset hyperactive delirium beside aggression, paranoia, and vivid auditory and visual hallucinations. Once diphenhydramine was discontinued, adjectives symptoms resided.(5)
Another case report describes a patient having cyproheptadine added to their phenelzine analysis in an attempt to relieve the patients anorgasmia. The patient began to suddenly experience ocular hallucination after taking the cyproheptadine for two months. Once the medication was terminated, the hallucinations stopped occurring in 48 hours Source(s): Medscape.com drug interaction checker
For the congestion you can use saline nasal spray as often as needed. A cool-mist humidifier will help beside the sore throat, as will sucking on hard candies. Tylenol or Advil would be fine for the body aches. Do not use Excedrin, as the caffeine in Excedrin is contraindicated while using MAOIs. Source(s): PharmD nominee
Call a pharmacist...
Related Questions: