How long does it run for your body to stop making serotonin on antidepressant ?
I know if you take it too long, your body stops making its own serotonin, but how long is that?
Answers:
Doc is correct, and your teacher may want to invest surrounded by a pharmacology handbook. There are a few types of antidepressants, but I think she is talking something like SSRIs (Zoloft, Paxil, Prozac, etc). These work, just like Doc said, by affecting where serotonin hang out. The abbreviation SSRI stands for Selective Serotonin Reuptake Inhibitor, which is a fancy way of saying it keep serotonin from being sucked back up by the nerve ending that released it. But it has no effect on how much serotonin is produced. Source(s): PharmD candidate
It does not. An antidepressant affects the serotonin equilibrium. Serotonin is either in the brain's liquid or it is attached to serotonin receptors within brain cells. It leaves receptors and return and leaves, etc etc. in the normal entity. In depressed people it tends to spend too much time attached to receptors. Antidepressants lock onto receptors and slow or inhibit serotonin re-uptake by the receptors
There is plenty of misleading information on this question. First, antidepressants affect brain serotonin (that's why they are prescribed). However, your teacher is misinterpreting core neurophysiology and neuropharmacology. Clinically depressed patients have a decrease in the functional flurry of monoamines, including serotonin (the other monoamines include norepinephrine and dopamine). It is pretty clear from the last 30+ years of clinical research that depression is directly related to serotonin in one of several ways: any not enough serotonin is being produced and/or released, or there is down regulation of serotonin receptor density or down regulation of serotonin receptor sensitivity. Common classes of antidepressants (e.g., SSRIs, MAOIs) remedy this by increasing the functional stir of the serotonin system. This is accomplished different ways but basically they each turn rotten the brain's natural turning off mechanism to net whatever serotonin is available more effective. Here's how: Normally, many neurochemicals when released from neurons fashion brief contact with nearby receptors which in turn any cause an increase or decrease in release of some other neurochemical stored contained by that neuron. This process is often turned off by something called reuptake (wherein the neurotransmitter is removed from the synapes so it cannot verbs to interact with receptors). This ballet occurs millions of times a second contained by the brain. SSRIs block the reuptake (removal) of serotonin. If reuptake back into the neuron is blocked, it allows more serotonin-receptor interaction. Similarly, MAOIs accomplish the same end result but contained by a different way. Another way the brain turns off serotonin (and some other neurotransmitters) is through enzymatic destruction by an enzyme call monoamine oxidase) MAO). MAO inhibitors (MAOIs) inhibit MAO. By inhibiting the enzyme that breaks down serotonin, more serotonin is available to interact with serotonin receptors). None of these actions would decrease the assembly of serotonin (and yes, I have considered presynaptic inhibitory feedback loops).
It would make little sense if antidepressants decreased the capability of the brain to synthesize serotonin since the lack of serotonin (as discussed above) is an important cause of the depression person treated by the antidepressant! That thinking is simply illogical. Sorry. Source(s): I am a forensic psychopharmacologist, author of several textbooks, over 100 articles on drugs, the brain and behavior, taught clinical psychopharmacology for tons years.
Michelle is correct. These drugs do not in any style alter the production of serotonin. What it does is to affect the re-uptake of the serotonin at the post synaptic neuron. This has the effect of increasing function of serotonin and thus will affect mood. This process is called potentiating the serotonin.
Your body doesn't stop making serotonin. If that were true, your brain would stop working. Serotonin is a neurochemical critical for brain function. Source(s): I'm an RN.
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Doc is correct, and your teacher may want to invest surrounded by a pharmacology handbook. There are a few types of antidepressants, but I think she is talking something like SSRIs (Zoloft, Paxil, Prozac, etc). These work, just like Doc said, by affecting where serotonin hang out. The abbreviation SSRI stands for Selective Serotonin Reuptake Inhibitor, which is a fancy way of saying it keep serotonin from being sucked back up by the nerve ending that released it. But it has no effect on how much serotonin is produced. Source(s): PharmD candidate
It does not. An antidepressant affects the serotonin equilibrium. Serotonin is either in the brain's liquid or it is attached to serotonin receptors within brain cells. It leaves receptors and return and leaves, etc etc. in the normal entity. In depressed people it tends to spend too much time attached to receptors. Antidepressants lock onto receptors and slow or inhibit serotonin re-uptake by the receptors
There is plenty of misleading information on this question. First, antidepressants affect brain serotonin (that's why they are prescribed). However, your teacher is misinterpreting core neurophysiology and neuropharmacology. Clinically depressed patients have a decrease in the functional flurry of monoamines, including serotonin (the other monoamines include norepinephrine and dopamine). It is pretty clear from the last 30+ years of clinical research that depression is directly related to serotonin in one of several ways: any not enough serotonin is being produced and/or released, or there is down regulation of serotonin receptor density or down regulation of serotonin receptor sensitivity. Common classes of antidepressants (e.g., SSRIs, MAOIs) remedy this by increasing the functional stir of the serotonin system. This is accomplished different ways but basically they each turn rotten the brain's natural turning off mechanism to net whatever serotonin is available more effective. Here's how: Normally, many neurochemicals when released from neurons fashion brief contact with nearby receptors which in turn any cause an increase or decrease in release of some other neurochemical stored contained by that neuron. This process is often turned off by something called reuptake (wherein the neurotransmitter is removed from the synapes so it cannot verbs to interact with receptors). This ballet occurs millions of times a second contained by the brain. SSRIs block the reuptake (removal) of serotonin. If reuptake back into the neuron is blocked, it allows more serotonin-receptor interaction. Similarly, MAOIs accomplish the same end result but contained by a different way. Another way the brain turns off serotonin (and some other neurotransmitters) is through enzymatic destruction by an enzyme call monoamine oxidase) MAO). MAO inhibitors (MAOIs) inhibit MAO. By inhibiting the enzyme that breaks down serotonin, more serotonin is available to interact with serotonin receptors). None of these actions would decrease the assembly of serotonin (and yes, I have considered presynaptic inhibitory feedback loops).
It would make little sense if antidepressants decreased the capability of the brain to synthesize serotonin since the lack of serotonin (as discussed above) is an important cause of the depression person treated by the antidepressant! That thinking is simply illogical. Sorry. Source(s): I am a forensic psychopharmacologist, author of several textbooks, over 100 articles on drugs, the brain and behavior, taught clinical psychopharmacology for tons years.
Michelle is correct. These drugs do not in any style alter the production of serotonin. What it does is to affect the re-uptake of the serotonin at the post synaptic neuron. This has the effect of increasing function of serotonin and thus will affect mood. This process is called potentiating the serotonin.
Your body doesn't stop making serotonin. If that were true, your brain would stop working. Serotonin is a neurochemical critical for brain function. Source(s): I'm an RN.
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