Does Prozac enjoy any denial interactions near Vicodin?

I had a lot of caffeine yesterday - not any more than I usually do, and have one of the worst panic attacks of my life. I started Prozac recently and haven't have caffeine since then, so I can only guess it was a Prozac/caffeine interaction. I want to be more thorough about drug interactions, so I was wondering if it's okay to be taking both Prozac and Vicodin?
Answers:
Prozac can decrease the worth of hydrocodone (one of the active ingredients in Vicodin) The Prozac can inhibit the hepatic metabolism of the hydrocodone to it's active metabolite, cause it to be less effective. Source(s): Epocrates
Prozac does not necessarily interact with hydrocodone (active ingredient within Vicodin,) but both of them--and the acetaminophen in Vicodin are all metabolized by the same enzyme group surrounded by the liver; the P450 pathway.
This may make the normal dose of Vicodin that you take grain stronger and last a bit longer--the same effect could actually be induced by drinking grapefruit juice, so spawn sure that you stay away from grapefruit juice and alcohol to avoid any further interactions. The current list only includes oxycodone--but adjectives opiates that undergo hepatic metabolism (in the liver) into morphine are subject to some of the first-pass effects--like P450 inhibition.
And as with all medicine that contain acetaminophen (Tylenol, or paracetamol) avoid alcohol! Source(s): http://en.wikipedia.org/wiki/Prozac#Inte…
http://en.wikipedia.org/wiki/Grapefruit_…
http://en.wikipedia.org/wiki/List_of_dru…
You need to talk with your pharmacist or physician formerly mixing Prozac and Vicodin. I would also strongly suggest that you be mindful of the use of Vicodin, which can be addictive, in consideration of your condition(s) which is being treated with Prozac. There is a stong correlation between depression, social phobia, and substance foul language. Be careful to take your medications solitary as prescribed and find a counselor, minister, or life coach whom you trust and can be honest with about your natural life circumstances and your inner self. Be well. Source(s): https://members.kaiserpermanente.org/kpweb/drugency/drugdetails.do?drugID=279552#Drug%20interactions

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