Plasma vs. Packed Cells?

When transfusing an individual with blood that is compatible but not the same type, it is esteemed to separate packed cells from the plasma and administer only the heaving cells. Why do you think this is done?
For two reasons:
(1) Often patients obligation only the rbc's, and not the extra volume of a unit of whole blood, and
(2) The plasma contains antibodies that could act in response with the recipient's rbc's. For example, if a patient with type A blood receive a unit of type O blood, the plasma of the type O blood contains anti-A antibodies. These Abs could react with the patient's rbc's.
The root is that the donor's plasma contains antibodies that might react adversely with the recipient.

However, most donated blood is fractionated into cell, various plasma proteins, platelets and serum. This way, a single donation may be used to treat a number of patients who merely need specific components of the blood. Source(s): I am a physiologist.

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