Can someone give a hand me trade name this diagnosis?
A 4 year old girl is brought to the ER because of a 5 day history of fever, diffuse abdominal twinge, nausea, vomitting and diarrhea. Examination shows patechie, and hepatosplenomegaly. Hemoglobin concentration is 8.7g/dL and platelet count is 60,000/mm3. A peripheral blood smear shows erythrocyte fragmantation. Which of the following renal findings is most likely to be associated with her condition?
a. Glomerular crescent formation
b. IgG-associated glomerular underground store membrane antibody
c. Membranoproliferative glomerulonephritis
d. Narrowing of the capillary wall by fibrin deposition
e. Periglomerular granuloma with giant cells
What is the diagnosis first, and what do you guys think the answer is??
Answers:
The most plausible diagnosis is hemolytic-uremic syndrome caused by gastroenteritis due to E. coli O157:H7.
The usual findings at biopsy are (d.) narrowing of the capillary wall by fibrin deposition. Source(s): I'm a retired pediatrician. I also checked my memory in Oski's Pediatrics, third edition, page 2205.
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a. Glomerular crescent formation
b. IgG-associated glomerular underground store membrane antibody
c. Membranoproliferative glomerulonephritis
d. Narrowing of the capillary wall by fibrin deposition
e. Periglomerular granuloma with giant cells
What is the diagnosis first, and what do you guys think the answer is??
Answers:
The most plausible diagnosis is hemolytic-uremic syndrome caused by gastroenteritis due to E. coli O157:H7.
The usual findings at biopsy are (d.) narrowing of the capillary wall by fibrin deposition. Source(s): I'm a retired pediatrician. I also checked my memory in Oski's Pediatrics, third edition, page 2205.
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