MCQ How does ursodeoxycholic bitter sharp prevent gallstones?
a. addition of bilirubin to bile
b. decrease in concentration of bile acids
c. fade away in the ratio of cholesterol to bile acids
d. increase in the ability of the gallbladder to concentrate bile
e. increase surrounded by the concentration of lecithin in bile
Answers:
c. decrease in the ratio of cholesterol to bile acids
Bile salt like ursodeoxycholic acid are absorbed and be in motion from the liver to the gall bladder where they are incorporated into bile. The ratio of bile salts to cholesterol and to lecithin regulates the formation of gallstones.
C. Since it decrease the rate that the intestines absorbs cholesterol, UDCA decreases the amount of cholesterol absorbed next to respect to bile acids.
A. is wrong because bilirubin is a metabolic component of heme catabolism
B. is wrong because UDCA is a type of bile acid
D. is wrong because this depends on properties of the epithelial cells in the gallbladder. (I believe a Na+ is used by these cell then allowing passive diffusion of water from the lumen of the gallbladder, thus concentrating the bile). Plus, more concentrated bile would exacerbate the problem.
E. Does not apply Source(s): http://en.wikipedia.org/wiki/Ursodeoxych…
Ursodeoxycholic tart helps regulate cholesterol by reducing the rate at which the intestine absorbs cholesterol molecules while breaking up micelles containing cholesterol. As a drug, it reduces cholesterol digestion and is used to dissolve (cholesterol) gallstones in patients who want an alternative to surgery.
Answer is (C). Source(s): http://en.wikipedia.org/wiki/Ursodeoxych…
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b. decrease in concentration of bile acids
c. fade away in the ratio of cholesterol to bile acids
d. increase in the ability of the gallbladder to concentrate bile
e. increase surrounded by the concentration of lecithin in bile
Answers:
c. decrease in the ratio of cholesterol to bile acids
Bile salt like ursodeoxycholic acid are absorbed and be in motion from the liver to the gall bladder where they are incorporated into bile. The ratio of bile salts to cholesterol and to lecithin regulates the formation of gallstones.
C. Since it decrease the rate that the intestines absorbs cholesterol, UDCA decreases the amount of cholesterol absorbed next to respect to bile acids.
A. is wrong because bilirubin is a metabolic component of heme catabolism
B. is wrong because UDCA is a type of bile acid
D. is wrong because this depends on properties of the epithelial cells in the gallbladder. (I believe a Na+ is used by these cell then allowing passive diffusion of water from the lumen of the gallbladder, thus concentrating the bile). Plus, more concentrated bile would exacerbate the problem.
E. Does not apply Source(s): http://en.wikipedia.org/wiki/Ursodeoxych…
Ursodeoxycholic tart helps regulate cholesterol by reducing the rate at which the intestine absorbs cholesterol molecules while breaking up micelles containing cholesterol. As a drug, it reduces cholesterol digestion and is used to dissolve (cholesterol) gallstones in patients who want an alternative to surgery.
Answer is (C). Source(s): http://en.wikipedia.org/wiki/Ursodeoxych…
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