The usefulness of matched control within study design?
Answers:
None, the big pharmaceutical industry has lobbied the FDA to implement those sorts of protocols to make studies more expensive and prevent start ups from competing.
It helps to decrease the influence of confounding variables in studies. For instance, if one of the test group is very overweight and not a soul in the control group is, it may appear that something that happens to that person surrounded by the test group is due to whatever it is you're testing, a bit than due to something with them. If you have a matched control, and the thing still happen it shows that it probably is due to the treatment and not due to something separate.
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