Does routine cbc detect sickle cell?
Answers:
It won't make a definite diagnosis, but it may suggest it. A cbc, which is a complete blood count may show whether or not the person have hemolytic anemia, which is a form of anemia due to destruction of red blood cells in the body. In this case the red blood cell count will be reduced, and the number of band (which are newly forming red blood cells) will be increased. Even though sickle cell is a form of hemolytic anemia, there are a number of other cause of hemolytic anemia out there. The way SCD is diagnosed is by a blood smear, where a pathologist in truth examines a drop of your blood under a microscope, looking for sickle-shaped red blood cells. Even better way to diagnose it is by DNA electrophoresis, where on earth they look for a one-point mutation of an amino acid valine into glutamate on the Beta chain of hemoglobin molecule Source(s): SGU Medical School
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