What is the difference between aspirin and paracetamol?
1. (as above)
2. Which category(aspirin/paracetamol) does panadol and tylenol fall under?
Thanks in finance!! :D
Answers:
1. Aspirin and paracetamol are both used as mild analgesics (painkillers) and antipyretics (fever-reducing), but their other effects differ. Aspirin reduces inflammation, which paracetamol does not, and so aspirin is often spoken of as a non-steroidal anti-inflammatory drug (NSAID). Aspirin has an effect on blood platelets, preventing them aggregating. This is a adjectives effect on preventing clotting in the coronary arteries causing a heart attack, so low dose aspirin is prescribed to individuals at risk of coronary events. Aspirin works by preventing the generation of prostaglandins, which are chemicals cause inflammatory reactions. Paracetamol does not share this property. Indeed its mode of action is still under discussion, but it probably works on the whole on receptors in the brain.
Which is the better drug? Both are effective for milder pains (headaches, bruises, early arthritis) and aspirin is unambiguously better if the pain is associated with inflammation, but otherwise it is a question of which side-effects are influential to any individual. Aspirin should never be given to children, because of the possibility of Reye's syndrome, a rare but very dangerous basis of coma and death. It is also apt to cause gastric irritation. On the other hand contained by overdose aspirin is far safer and easier to treat than paracetamol. Paracetamol overdose is one of the major causes of liver failure.
2. Panadol is a trade cross for paracetamol. Tylenol is a (North American) trade name for a series of tablets containing combinations of paracetamol (known as acetaminophen in the USA), codeine and caffeine in varying amounts. At lowest possible one similar combination is available in the UK (Syndol), but I am not going to recommend it. Source(s): 38 years in medicine
1. They are both non-steroidal anti-inflammatory drugs however paracetamol is kinder on the stomach than aspirin. Since aspirin is an anti-inflammatory it irreversibly inhibits the cyclooxygenase enzyme to be precise used to convert arachodonic acid to prostaglandins. Since prostaglandins sensitise sensory nerves inhibition of this will prevent pain however it will also cause stomach ulcer because it thins the mucosal lining of the stomach by preventing prostaglandin synthesis. Paracetamol however is a non-competitive inhibitor of the cyclooxygenase enzyme and it mops up the free radicals needed as a cofactor for prostaglandin synthesis which prevents the sensitisation of sensory nerves and therefore anguish.
I hope that helps and i am sorry but i don't know the answer to question 2. Try looking in ring and dale pharmacology it is a good source to use.
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2. Which category(aspirin/paracetamol) does panadol and tylenol fall under?
Thanks in finance!! :D
Answers:
1. Aspirin and paracetamol are both used as mild analgesics (painkillers) and antipyretics (fever-reducing), but their other effects differ. Aspirin reduces inflammation, which paracetamol does not, and so aspirin is often spoken of as a non-steroidal anti-inflammatory drug (NSAID). Aspirin has an effect on blood platelets, preventing them aggregating. This is a adjectives effect on preventing clotting in the coronary arteries causing a heart attack, so low dose aspirin is prescribed to individuals at risk of coronary events. Aspirin works by preventing the generation of prostaglandins, which are chemicals cause inflammatory reactions. Paracetamol does not share this property. Indeed its mode of action is still under discussion, but it probably works on the whole on receptors in the brain.
Which is the better drug? Both are effective for milder pains (headaches, bruises, early arthritis) and aspirin is unambiguously better if the pain is associated with inflammation, but otherwise it is a question of which side-effects are influential to any individual. Aspirin should never be given to children, because of the possibility of Reye's syndrome, a rare but very dangerous basis of coma and death. It is also apt to cause gastric irritation. On the other hand contained by overdose aspirin is far safer and easier to treat than paracetamol. Paracetamol overdose is one of the major causes of liver failure.
2. Panadol is a trade cross for paracetamol. Tylenol is a (North American) trade name for a series of tablets containing combinations of paracetamol (known as acetaminophen in the USA), codeine and caffeine in varying amounts. At lowest possible one similar combination is available in the UK (Syndol), but I am not going to recommend it. Source(s): 38 years in medicine
1. They are both non-steroidal anti-inflammatory drugs however paracetamol is kinder on the stomach than aspirin. Since aspirin is an anti-inflammatory it irreversibly inhibits the cyclooxygenase enzyme to be precise used to convert arachodonic acid to prostaglandins. Since prostaglandins sensitise sensory nerves inhibition of this will prevent pain however it will also cause stomach ulcer because it thins the mucosal lining of the stomach by preventing prostaglandin synthesis. Paracetamol however is a non-competitive inhibitor of the cyclooxygenase enzyme and it mops up the free radicals needed as a cofactor for prostaglandin synthesis which prevents the sensitisation of sensory nerves and therefore anguish.
I hope that helps and i am sorry but i don't know the answer to question 2. Try looking in ring and dale pharmacology it is a good source to use.
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