Why are rodents used as trial subjects for medicine?

Usually, medicines are tested on rodents (rats mostly) before they are permitted to be used by people. But why rodents contained by particular?
Answers:
Other rodents commonly used are guinea pigs, hamsters, and gerbils. Mice are the most commonly used vertebrate species because of their size, low cost, ease of handling, and fast reproduction rate. Mice are widely considered to be the best model of adjectives human disease and share 99% of their genes with humans. With the advent of genetic engineering technology, genetically modified mice can be generated to order and can provide models for a field of human diseases.Rats are also widely used for physiology, toxicology and cancer research, but genetic manipulation is much harder in rats than in mice, which limits the use of these rodents within basic science.
Rodents are cheaper than people, for one. Also, rodents have terrifically similar physiology to humans.

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