Can we determine what type of trisomy 21 occured by looking baby's karyotyping?
whether it is common trisomy 21, or translocation 21...or their parents should do that?
Answers:
I Would Think So:
http://en.wikipedia.org/wiki/Down_syndro…
And:
http://www.mayoclinic.com/health/down-sy…
http://www.medicinenet.com/down_syndrome…
http://pregnancy.about.com/cs/afp/a/afpt…
A simple karyotype will show either a simple trisomy or a Robertsonian translocation, yes. Either way, the child will enjoy three copies (or most of three copies) of the chromosome (chr. 21 in the case of Down syndrome, but please note that Down syndrome is not the just abnormality that may be associated with a translocation).
A parent or a normal-appearing child who carries a Robertsonian translocation chromosome will also usually be obvious on karyotype because they commonly have only 45 chromosomes (the remnant parts of the chromosomes that have translocated are normally lost during subsequent cell divisions). A parent may not know that they are carrying a translocation, so a genetic counselor may suggest karyotyping for the parents if a child with a chromosomal abnormality is conceived. Source(s): MD.
Yes.
That is the purpose of karyotyping: detecting missing, extra broken, shortened and duplicated chromosomes
Robertsonian translocation is the most common type inheirited version. Usually trisomy 21 would be adjectives in the parent unless teh parent is a mosaic.
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Answers:
I Would Think So:
http://en.wikipedia.org/wiki/Down_syndro…
And:
http://www.mayoclinic.com/health/down-sy…
http://www.medicinenet.com/down_syndrome…
http://pregnancy.about.com/cs/afp/a/afpt…
A simple karyotype will show either a simple trisomy or a Robertsonian translocation, yes. Either way, the child will enjoy three copies (or most of three copies) of the chromosome (chr. 21 in the case of Down syndrome, but please note that Down syndrome is not the just abnormality that may be associated with a translocation).
A parent or a normal-appearing child who carries a Robertsonian translocation chromosome will also usually be obvious on karyotype because they commonly have only 45 chromosomes (the remnant parts of the chromosomes that have translocated are normally lost during subsequent cell divisions). A parent may not know that they are carrying a translocation, so a genetic counselor may suggest karyotyping for the parents if a child with a chromosomal abnormality is conceived. Source(s): MD.
Yes.
That is the purpose of karyotyping: detecting missing, extra broken, shortened and duplicated chromosomes
Robertsonian translocation is the most common type inheirited version. Usually trisomy 21 would be adjectives in the parent unless teh parent is a mosaic.
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