Is the dose for Cefazolin 1 gram IV q 8 surrounded by a 70 kg manly next to a serum creatinine of 7.8mg% appropriate?


Answers:
That's kind of high. I'd be tempted to drop down to q12. If the long-suffering is on dialysis, then further adjustments might be needed.
Since two grams every 12 hours (4 grams per day) is listed as a usable dose surrounded by kidney failure, I don't think 1 gram Q8H (3 grams per day) would be excessive.
Here is a Univ of Cal San Fran guide hat suggests a lower dose:
http://clinicalpharmacy.ucsf.edu/idmp/va…
7.8 creat would approximately be a GFR of 12
(skip to page 20)

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