A drug that blocked the enzyme aromatase would do what to a merciful?

A) bring on symptoms of menopause
B) reduce the risk of breast cancer
C) prevent the synthesis of estrogen
D) increase the risk of osteoporosis
E) all of the above

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Answers:

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Aromatase is the enzyme which is responsible for the biosynthesis of estrogens.

Androstenedione ---(aromatase)--> Estrone
Testosterone ---(aromatase)---> Estradiol

Aromatase inhibitors like anastrozole and letrozole prevent aromatase from converting androgens into estrogens resulting surrounded by low estrogen levels.

Low estrogen levels will contribute to E) All of the above.

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Tamoxifen is the first drug of this type marketed for the fall of breast cancer risk.
Aromatase converts androgens to estrogens.
Estrogens prevent the symptoms of menopause
Estrogens helps tp prevent osteoporosis

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Your answer is E) All of the Above

P.S. Taxomifen is NOT an aromatase inhibitor, it is a selective estrogen receptor modulator. Source(s): I'm a medical oncology nurse.

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