What effect does grapefruit hold on medication?

I've noticed that quite a few medications specify that you can't own grapefruit while you're taking it, from heart meds to anxiety meds.

What effect does grapefruit have on medication?
Answers:
Thank you for the question. An EXCELLENT question, I may add on.

Grape fruit juice can inhibit a group of enzymes in the liver called the cytochrome P450 mixed function oxygenases, which are simply enzymes that metabolize (and thus clear from the body) frequent drugs.

Thus, grape fruit juice can both increase the blood levels of and prolong the action of drugs. This can hold dangerous consequences in terms of side effects. Source(s): My remote medical training.
it effects how the medication is held in the system. it binds to an enzyme which reduces the absorption of dependable medications. When grapefruit juice blocks the enzyme, it’s easier for the medication to pass from your tummy to your bloodstream. your blood level could rise faster and higher than normal, and in some cases the unusually high levels can be dangerous. Source(s): me...CphT (certified pharmacy tech)

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