Doxepin is an antidepressant beside H2 antagonist properties. Does it enjoy GI effects?
H2 antagonism reduces gastric acid secretion. Zantac, Tagamet, and a couple others are used to treat heartburn.
Does doxepin's H2 antagonism reduce gastric acerbic secretion in a similar way? Would it make for an influential heartburn medication?
Answers:
Yes, it could be used to treat ulcers, but it isn't good for GERD because of its anticholinergic properties, so it may make heartburn worse instead of better. There's little object to use it for that purpose at any rate, simply because of the better alternatives you listed.
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Does doxepin's H2 antagonism reduce gastric acerbic secretion in a similar way? Would it make for an influential heartburn medication?
Answers:
Yes, it could be used to treat ulcers, but it isn't good for GERD because of its anticholinergic properties, so it may make heartburn worse instead of better. There's little object to use it for that purpose at any rate, simply because of the better alternatives you listed.
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