What are the chemical reaction involved within the body after taking Eltroxin tablet?
For last 30 years I have been taking Eltroxin (100 mg) 1.5 tab daily for my thyroid Problem.I want to know the reactions going on inside my body and if it is leaving any continuing effect.
Answers:
How does it work?
Eltroxin tablets contain the active ingredient levothyroxine sodium (previously known simply as thyroxine sodium in the UK). (NB. Levothyroxine is also available in need a brand name, ie as the generic medicine.) Levothyroxine is the same as the hormone thyroxine, which is produced fluently by the thyroid gland.
The thyroid gland produces and releases two thyroid hormones: thyroxine (T4) and tri-iodothyronine (T3). Tri-iodothyronine is the more active thyroid hormone, and thyroxine is converted into T3 in various parts of the body. These hormones are responsible for maintain a normal rate of metabolism in the body.
When the thyroid gland is unable to produce middle-of-the-road amounts of thyroxine, the level of both thyroid hormones in the blood decreases (hypothyroidism). This results contained by a reduced rate of metabolism, leading to symptoms such as weight gain, intolerance to cold and tiredness.
Levothyroxine tablets are given to replace the thyroxine that would normally be produced fluently by the thyroid gland. This returns levels of T3 and T4 to normal.
Once the thyroid gland becomes powerless to produce thyroxine, it will generally not return to normal function. This means that once thyroxine replacement is started, it usually wants to be taken for the rest of a person’s life.
The daily dose should preferably be taken before breakfast.
What is it used for?
Underproduction of thyroid hormones by the thyroid gland (hypothyroidism).
Warning!
You will inevitability to have regular blood tests to monitor your levels of thyroid hormones while taking this pills. This will enable your doctor to prescribe you the correct dose to increase levels of your thyroid hormones into the normal list.
Certain medicines can interfere with blood tests that you own to determine your thyroid hormone levels (thyroid function tests). It is important to inform your doctor of all the medicine you are taking prior to and at the time of blood tests.
Use with caution contained by
Elderly people.
Heart disease such as angina, heart failure, irregular heartbeats, or history of heart attack.
Any condition causing decrease function of the adrenal glands.
Decreased production of all hormones by the pituitary gland (panhypopituitarism).
Diabetes mellitus.
Rare disease where there is a problem next to the kidneys that causes large amounts of dilute urine to be produced (diabetes insipidus).
Not to be used in
Overproduction of thyroid hormones by the thyroid gland (thyrotoxicosis).
This pills should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.If you feel you have experienced an allergic antipathy, stop using this medicine and inform your doctor or pharmacist immediately.
Pregnancy and breastfeeding
Certain medicines should not be used during pregnancy or breastfeeding. However, other medicine may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, previously using any medicine.
Levothyroxine can be taken during pregnancy. However, it is important that pregnant women have regular blood test to monitor their levels of thyroid hormones during the pregnancy. Thyroid hormones can cross the placenta and excessive levels can be harmful to the developing babe-in-arms, so it is important to ensure that you are taking the correct dose. Most women whose thyroid hormone levels are in the average range when they fall pregnant will not need any dose adjustment of their levothyroxine. Seek medical advice from your doctor.
Thyroid hormones pass into breast milk, but in amounts that are too small to affect the nursing babe, or to affect tests for neonatal hypothyroidism. It is safe for women taking this medicine to breastfeed their babies. Seek further medical guidance from your doctor.
Side effects
Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated next to this medicine. Just because a side effect is stated here does not mean that all ethnic group using this medicine will experience that or any side effect.
Side effects caused by levothyroxine usually only materialize if your dose is too high. For this reason, you should tell your doctor if you procure any of the following side effects:
chest pain (angina)
awareness of your heart beat (heart palpitations)
abnormal heart beat (arrhythmias)
faster than normal heart beat (tachycardia)
muscle cramps
diarrhoea
vomiting
shaking, usually of the hands (tremor)
restlessness
excitability
difficulty contained by sleeping (insomnia)
headache
flushing
sweating
fever
intolerance to heat
muscle weakness
substance loss.
The side effects listed above may not include all of the side effects reported by the medicine's manufacturer.For more information going on for any other po Source(s): Patterson S, Jones B. 2006. Bioequivalence and Statistics in Clinical Pharmacology. Florida:Chapman and Hall CRC. Pg 30
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Answers:
How does it work?
Eltroxin tablets contain the active ingredient levothyroxine sodium (previously known simply as thyroxine sodium in the UK). (NB. Levothyroxine is also available in need a brand name, ie as the generic medicine.) Levothyroxine is the same as the hormone thyroxine, which is produced fluently by the thyroid gland.
The thyroid gland produces and releases two thyroid hormones: thyroxine (T4) and tri-iodothyronine (T3). Tri-iodothyronine is the more active thyroid hormone, and thyroxine is converted into T3 in various parts of the body. These hormones are responsible for maintain a normal rate of metabolism in the body.
When the thyroid gland is unable to produce middle-of-the-road amounts of thyroxine, the level of both thyroid hormones in the blood decreases (hypothyroidism). This results contained by a reduced rate of metabolism, leading to symptoms such as weight gain, intolerance to cold and tiredness.
Levothyroxine tablets are given to replace the thyroxine that would normally be produced fluently by the thyroid gland. This returns levels of T3 and T4 to normal.
Once the thyroid gland becomes powerless to produce thyroxine, it will generally not return to normal function. This means that once thyroxine replacement is started, it usually wants to be taken for the rest of a person’s life.
The daily dose should preferably be taken before breakfast.
What is it used for?
Underproduction of thyroid hormones by the thyroid gland (hypothyroidism).
Warning!
You will inevitability to have regular blood tests to monitor your levels of thyroid hormones while taking this pills. This will enable your doctor to prescribe you the correct dose to increase levels of your thyroid hormones into the normal list.
Certain medicines can interfere with blood tests that you own to determine your thyroid hormone levels (thyroid function tests). It is important to inform your doctor of all the medicine you are taking prior to and at the time of blood tests.
Use with caution contained by
Elderly people.
Heart disease such as angina, heart failure, irregular heartbeats, or history of heart attack.
Any condition causing decrease function of the adrenal glands.
Decreased production of all hormones by the pituitary gland (panhypopituitarism).
Diabetes mellitus.
Rare disease where there is a problem next to the kidneys that causes large amounts of dilute urine to be produced (diabetes insipidus).
Not to be used in
Overproduction of thyroid hormones by the thyroid gland (thyrotoxicosis).
This pills should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.If you feel you have experienced an allergic antipathy, stop using this medicine and inform your doctor or pharmacist immediately.
Pregnancy and breastfeeding
Certain medicines should not be used during pregnancy or breastfeeding. However, other medicine may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, previously using any medicine.
Levothyroxine can be taken during pregnancy. However, it is important that pregnant women have regular blood test to monitor their levels of thyroid hormones during the pregnancy. Thyroid hormones can cross the placenta and excessive levels can be harmful to the developing babe-in-arms, so it is important to ensure that you are taking the correct dose. Most women whose thyroid hormone levels are in the average range when they fall pregnant will not need any dose adjustment of their levothyroxine. Seek medical advice from your doctor.
Thyroid hormones pass into breast milk, but in amounts that are too small to affect the nursing babe, or to affect tests for neonatal hypothyroidism. It is safe for women taking this medicine to breastfeed their babies. Seek further medical guidance from your doctor.
Side effects
Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated next to this medicine. Just because a side effect is stated here does not mean that all ethnic group using this medicine will experience that or any side effect.
Side effects caused by levothyroxine usually only materialize if your dose is too high. For this reason, you should tell your doctor if you procure any of the following side effects:
chest pain (angina)
awareness of your heart beat (heart palpitations)
abnormal heart beat (arrhythmias)
faster than normal heart beat (tachycardia)
muscle cramps
diarrhoea
vomiting
shaking, usually of the hands (tremor)
restlessness
excitability
difficulty contained by sleeping (insomnia)
headache
flushing
sweating
fever
intolerance to heat
muscle weakness
substance loss.
The side effects listed above may not include all of the side effects reported by the medicine's manufacturer.For more information going on for any other po Source(s): Patterson S, Jones B. 2006. Bioequivalence and Statistics in Clinical Pharmacology. Florida:Chapman and Hall CRC. Pg 30
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