What permitted medication bring a false positive for opiates during drug conducting tests?
I work at a lab that is certified to do drug testing. Occasionally we do what we call rapidtox trial (on-site) where I just put simple drops of urine onto the test and hang around to read results in a few minutes (just like a pregnancy test). Twice in former times week I've had two different patients come out positive for opiates. When they come out positive we send the urine to our main lab for further conducting tests and confirmation. But it got me wondering what legal medications might effect false positives for opiates? How accurate are these types of drug tests any ways?
Answers:
YOu really do opiates don't you?
Sam's right. Big emphasis on the pain meds. Examples including Vicoden, Norco, Percocet, Percodan, Oxycodone, Hydrocodone, and some times (depending on the test) even Ultram. All of these are properly prescribed by physicians but will result in true positive opioid tests. Source(s): medical school, residency, family unit practice
Ok so I spent 5 years (while in graduate school) on the other side of this process. Meaning, that I was one of the associates at LabCorp who did those urine drug screens that were sent out.
Basically, the type of test that your Redox ( "contained by house style") test is similar to a method known as TLC (Thin Layer Chromatography). You are performing a qualitative non-specific test. This type exam is very subject to interferences, just due to the simplicity of it. All compounds are made up of elements which has a specific AMU (atomic mass weight). In the cases of analyzing compounds, and especially purely by groups (opiates, benzos, etc.) leaves a lat of room for polyatomic interferences, meaning that some compounds can come to gether and equal the amu of another drug compound. It is because of this high subjectivity to interferences, that it is protocol to confirm by sending out to a lab where it will be run via GC (Gas Chromatography) or GC-MS (Gas Chromatography-Mass Spectrometry). This are especially sensitive instruments that can monitor for multiple analytes at a time, including interferring compounds. Also these instruments are qualitative specific (meaning they identify the exact drug compound and not just its group) as well as quantitative (tells you exactly how much of the drug compound is present in the sample).
Opiates are some of the more suceptable groups for interferences. For example the drug Tramadol (Rx drug to be precise classed as an analgesic, but functions as a gamma opioid blocker as well as an SSRI and is used to treat pain) can very easily raison d`¨ētre someone to show up positive on your Redox test kit, for opiates, when technically it is not an opiate, just shares some similarity contained by structure, especially to methadone.
Then there are a lot of legal drugs that will show up on a drug trial. The opiate class of drugs for example includes many legal drugs, such as hydrocodone, oxycodone, pentazocine, hydromorphone, methadone, fentanyl, etc. All of these drugs are legal, but if a lenient shows up positive for opiates on your test (and they would if they were taking any of the above legal drugs) and next you sent it out for confirmation, then it would be narrowed down to which opiate drug was present, ad if this character could not produce a legal script for this medication, then it is just indistinguishable as taking an illegal drug. Source(s): Toxicologist
It be the poppy seeds on their bagel. Source(s): Didn't you ever watch Seinfeld?
For true false positive -
1. Commonest source is Poppy seeds and baked goods with illustrious concentration of poppy seeds.
2. Cough medicine with dextromethorphan
3. Nyquil
These are true positives that some population do not realize are actually narcotics
1. Most rx pain meds
2. Cough medication with codeine Source(s): I am a doctor
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Answers:
YOu really do opiates don't you?
Sam's right. Big emphasis on the pain meds. Examples including Vicoden, Norco, Percocet, Percodan, Oxycodone, Hydrocodone, and some times (depending on the test) even Ultram. All of these are properly prescribed by physicians but will result in true positive opioid tests. Source(s): medical school, residency, family unit practice
Ok so I spent 5 years (while in graduate school) on the other side of this process. Meaning, that I was one of the associates at LabCorp who did those urine drug screens that were sent out.
Basically, the type of test that your Redox ( "contained by house style") test is similar to a method known as TLC (Thin Layer Chromatography). You are performing a qualitative non-specific test. This type exam is very subject to interferences, just due to the simplicity of it. All compounds are made up of elements which has a specific AMU (atomic mass weight). In the cases of analyzing compounds, and especially purely by groups (opiates, benzos, etc.) leaves a lat of room for polyatomic interferences, meaning that some compounds can come to gether and equal the amu of another drug compound. It is because of this high subjectivity to interferences, that it is protocol to confirm by sending out to a lab where it will be run via GC (Gas Chromatography) or GC-MS (Gas Chromatography-Mass Spectrometry). This are especially sensitive instruments that can monitor for multiple analytes at a time, including interferring compounds. Also these instruments are qualitative specific (meaning they identify the exact drug compound and not just its group) as well as quantitative (tells you exactly how much of the drug compound is present in the sample).
Opiates are some of the more suceptable groups for interferences. For example the drug Tramadol (Rx drug to be precise classed as an analgesic, but functions as a gamma opioid blocker as well as an SSRI and is used to treat pain) can very easily raison d`¨ētre someone to show up positive on your Redox test kit, for opiates, when technically it is not an opiate, just shares some similarity contained by structure, especially to methadone.
Then there are a lot of legal drugs that will show up on a drug trial. The opiate class of drugs for example includes many legal drugs, such as hydrocodone, oxycodone, pentazocine, hydromorphone, methadone, fentanyl, etc. All of these drugs are legal, but if a lenient shows up positive for opiates on your test (and they would if they were taking any of the above legal drugs) and next you sent it out for confirmation, then it would be narrowed down to which opiate drug was present, ad if this character could not produce a legal script for this medication, then it is just indistinguishable as taking an illegal drug. Source(s): Toxicologist
It be the poppy seeds on their bagel. Source(s): Didn't you ever watch Seinfeld?
For true false positive -
1. Commonest source is Poppy seeds and baked goods with illustrious concentration of poppy seeds.
2. Cough medicine with dextromethorphan
3. Nyquil
These are true positives that some population do not realize are actually narcotics
1. Most rx pain meds
2. Cough medication with codeine Source(s): I am a doctor
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