What types of anemia are genetic and which are not?


Answers:
There are a number of congenital conditions that lead to anaemia, the commonest worldwide being Sickle Cell Anaemia. The majority of anaemias are however dietary due any to iron or folic acid deficiency. B12 or Pernicious anaemia sits somewhere in the middle, anyone due to changes in the immune system causing production of auto-antibodies. The predisposition to have this group of conditions is probably inherited. Source(s): GP for more years than I care to remember
Anemia is a lessening in normal number of red blood cells (RBCs) or smaller number than the normal quantity of hemoglobin in the blood. However, it can include decrease oxygen-binding ability of each hemoglobin molecule due to deformity or nouns in numerical development as in some other types of hemoglobin defect.
Sickle cell anemia is a disease passed down through families in which red blood cells form an deviant crescent shape. (Red blood cells are normally shaped like a disc.)
Thalassemia is an blood disorder passed down through family (inherited) in which the body makes an abnormal form of hemoglobin, the protein surrounded by red blood cells that carries oxygen. The disorder results in excessive destruction of red blood cell and anemia.
Fanconi's anemia is disease passed down through families (inherited) that mainly affects the bone marrow. It results in decrease production of all types of blood cells.
Fanconi's anemia is different from Fanconi syndrome, a rare kidney disorder.
Glucose-6-phosphate dehydrogenase (G-6-PD) negative amount is a hereditary condition in which red blood cells break down when the body is exposed to confident drugs or the stress of infection.
Iron deficiency anemia is the most common type of anemia overall and it has lots causes. RBCs often appear hypochromic (paler than usual) and microcytic (smaller than usual) when viewed next to a microscope.
# Megaloblastic anemia, the most common cause of macrocytic anemia, is due to a deficiency of any vitamin B12, folic acid (or both). Deficiency in folate and/or vitamin B12 can be due either to lacking intake or insufficient absorption. Folate deficiency normally does not produce neurological symptoms, while B12 fewer does.
* Pernicious anemia is caused by a lack of intrinsic factor. Intrinsic factor is required to absorb vitamin B12 from food. A denial of intrinsic factor may arise from an autoimmune condition targeting the parietal cells (atrophic gastritis) that produce intrinsic factor or against intrinsic factor itself. These lead to poor incorporation of vitamin B12.
* Macrocytic anemia can also be caused by removal of the functional portion of the stomach, such as during gastric bypass surgery, leading to reduced vit B12/folate absorption. Therefore one must other be aware of anemia following this procedure. Source(s): http://en.wikipedia.org/wiki/Anemia
http://www.medicinenet.com/anemia/articl…
http://www.merck.com/mmpe/sec11/ch129/ch…
http://www.nlm.nih.gov/medlineplus/ency/…
http://www.nlm.nih.gov/medlineplus/ency/…
http://www.nlm.nih.gov/medlineplus/ency/…
http://www.nlm.nih.gov/medlineplus/ency/…
http://www.nlm.nih.gov/medlineplus/ency/…

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