What drug interactions go off if the following are administered at one and the same time?
a)cimetidine and propranolol
b) phenelzine and broad beans or cheddar cheese
c) tetracyclines and antacids
d) alcohol and diazepam
e) warfarin and lots of cabbage
Answers:
The answers for all these questions will take a great deal of space so I've given links - where the interactions are explained.
a) Cimetidine and Propranolol
http://www.drugs.com/drug_interactions.p…
b) Phenelzine and broad beans and cheddar cheese.
Broad beans and cheddar cheese contain tyramine.
While you are taking phenelzine, you must not drink alcohol or eat foods that are high within tyramine.
Eating tyramine while you are taking phenelzine can raise your blood pressure to dangerous levels, cause symptoms that include sudden and severe headache, rapid heartbeat, stiffness in your neck, nausea, vomiting, cold sweat, reverie problems, and sensitivity to light. Stop taking phenelzine and call your doctor at once if you have any of these symptoms.
You should become greatly familiar with the list of foods and medicine you must avoid while you are taking phenelzine.
Phenelzine can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.
http://www.drugs.com/cg/low-tyramine-die…
c) Tetracyclines and Antacids. (I've used Gaviscon as an example surrounded by the interactions checker)
http://www.drugs.com/drug_interactions.p…
d) Alcohol and Diazepam
http://www.drugs.com/drug_interactions.p…
e) Warfarin and lots of cabbage (contains Vitamin K).
Vitamin K may antagonize the hypoprothrombinemic effect of oral anticoagulants. Vitamin K is a cofactor in the synthesis of blood clotting factors that are inhibited by oral anticoagulants, thus administration of vitamin K can reverse the dealing of oral anticoagulants.
MANAGEMENT: Intake of vitamin K through supplements or diet should not vary significantly during oral anticoagulant therapy. The International Normalization Ratio (INR) should be monitored and anticoagulant dosage adjusted as called for.
http://www.drugs.com/drug_interactions.p…
Avoid sudden changes in your diet. Vitamin K decreases the effects of warfarin. Large amounts of vitamin K are found surrounded by foods such as liver, broccoli, brussels sprouts, spinach, Swiss chard, coriander, collards, cabbage, and other green leafy vegetables. Do not change the amount of these foods in your diet without first discussion to your doctor.
http://www.drugs.com/warfarin.html
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b) phenelzine and broad beans or cheddar cheese
c) tetracyclines and antacids
d) alcohol and diazepam
e) warfarin and lots of cabbage
Answers:
The answers for all these questions will take a great deal of space so I've given links - where the interactions are explained.
a) Cimetidine and Propranolol
http://www.drugs.com/drug_interactions.p…
b) Phenelzine and broad beans and cheddar cheese.
Broad beans and cheddar cheese contain tyramine.
While you are taking phenelzine, you must not drink alcohol or eat foods that are high within tyramine.
Eating tyramine while you are taking phenelzine can raise your blood pressure to dangerous levels, cause symptoms that include sudden and severe headache, rapid heartbeat, stiffness in your neck, nausea, vomiting, cold sweat, reverie problems, and sensitivity to light. Stop taking phenelzine and call your doctor at once if you have any of these symptoms.
You should become greatly familiar with the list of foods and medicine you must avoid while you are taking phenelzine.
Phenelzine can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert.
http://www.drugs.com/cg/low-tyramine-die…
c) Tetracyclines and Antacids. (I've used Gaviscon as an example surrounded by the interactions checker)
http://www.drugs.com/drug_interactions.p…
d) Alcohol and Diazepam
http://www.drugs.com/drug_interactions.p…
e) Warfarin and lots of cabbage (contains Vitamin K).
Vitamin K may antagonize the hypoprothrombinemic effect of oral anticoagulants. Vitamin K is a cofactor in the synthesis of blood clotting factors that are inhibited by oral anticoagulants, thus administration of vitamin K can reverse the dealing of oral anticoagulants.
MANAGEMENT: Intake of vitamin K through supplements or diet should not vary significantly during oral anticoagulant therapy. The International Normalization Ratio (INR) should be monitored and anticoagulant dosage adjusted as called for.
http://www.drugs.com/drug_interactions.p…
Avoid sudden changes in your diet. Vitamin K decreases the effects of warfarin. Large amounts of vitamin K are found surrounded by foods such as liver, broccoli, brussels sprouts, spinach, Swiss chard, coriander, collards, cabbage, and other green leafy vegetables. Do not change the amount of these foods in your diet without first discussion to your doctor.
http://www.drugs.com/warfarin.html
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