How oodles 5 mg oxycodone would result surrounded by post mortem blood stratum of 0.23 mg/ml of oxycodone?

My husband committed suicide not by drug overdose but another method. The toxicology report found ethanol level of .157 gm%, 0.23 gm/ml of oxycodone and less than 0.05 micrograms/ml of oxymorphone. Would taking four 5 mg oxycodone result in this toxicology amount or would he own had to have taken more? Thanks for your help.

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Answers:

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First of adjectives, let me say that I'm very sorry for your loss.

It would come across to me that there is an error in the value you stated for the oxycodone blood height. Are you sure the amount was in mg/ml and not micrograms (mcg or ug) per ml? A 0.23 mg/ml value would be seemingly impossible to dig up.

Again, very sorry for your loss.

EDIT: According to a clinical pharmacology paper I found, the average maximum serum concentration for a 15mg dose of oxycodone is around 30-45 ng/ml. This translates to a serum concentration of roughly 10-15ng/ml per 5mg oral oxycodone. The math isn't perfect, but the amount within the report translates to 230ng/ml, so you can imagine the oral dose of oxycodone required to achieve a concentration of 230ng/ml is a lot more than four 5mg tablets.

A final details: oxymorphone is a metabolite of oxycodone metabolism, so given the oxymorphone concentration, it's likely that only oxycodone was taken fairly than two separate drugs.

That's about the best I can do. Sorry again. Source(s): Med student;
http://paincenter.wustl.edu/c/BasicResea…

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