Whats the difference between epinepherine and norepinephrine?
thankyou
Answers:
They are homologs. The structural difference is that epinephrine has a methyl group attached to its nitrogen, while the methyl group is replaced by a hydrogen atom in norepinephrine.
if you include a methyl group to the amine nitrogen of NE you get epinepherine.
The effects of NE are to stimulate alpha receptors, whereas epinepherine stimulates both Beta 1 and Beta 2 and also alpha receptors.
Beta 1 stimulation increases heart rate and force of contraction of the heart, Beta 2 causes dilation in blood vessel to improve blood flow to the muscles and also relaxes the muscles of the bronkial tree.
Alpha stimulation increased vascular resistance to cause a raise surrounded by blood pressure that indirectly causes a reflex slowing of the heart through increase vagal stimulation of acetyl choline secetion to the heart.
They are structurally similar, yet different by a methyl group.
Epinephrine is the primary adrenal cortex secretion and is thought of as more of a "hormone." Norepinephrine is an important neurotransmitter in the nervy system. Although it is also secreted by the adrenal gland, it is often more thought of as a "neurotransmitter" rather than a hormone (even though it does act as both).
They function roughly the same; they both speed up heart rate and heart contractility, they both slow down GI function, etc.
They are both broken down by COMT and MAO (catechol-O-methyl transferase and monoamine oxidase).
I'm sure there are more differences but those are the only that come to mind! Source(s): Pharmacy student
http://video.google.com/videosearch?q=fi…
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Question for nurses or folks who know?
Answers:
They are homologs. The structural difference is that epinephrine has a methyl group attached to its nitrogen, while the methyl group is replaced by a hydrogen atom in norepinephrine.
if you include a methyl group to the amine nitrogen of NE you get epinepherine.
The effects of NE are to stimulate alpha receptors, whereas epinepherine stimulates both Beta 1 and Beta 2 and also alpha receptors.
Beta 1 stimulation increases heart rate and force of contraction of the heart, Beta 2 causes dilation in blood vessel to improve blood flow to the muscles and also relaxes the muscles of the bronkial tree.
Alpha stimulation increased vascular resistance to cause a raise surrounded by blood pressure that indirectly causes a reflex slowing of the heart through increase vagal stimulation of acetyl choline secetion to the heart.
They are structurally similar, yet different by a methyl group.
Epinephrine is the primary adrenal cortex secretion and is thought of as more of a "hormone." Norepinephrine is an important neurotransmitter in the nervy system. Although it is also secreted by the adrenal gland, it is often more thought of as a "neurotransmitter" rather than a hormone (even though it does act as both).
They function roughly the same; they both speed up heart rate and heart contractility, they both slow down GI function, etc.
They are both broken down by COMT and MAO (catechol-O-methyl transferase and monoamine oxidase).
I'm sure there are more differences but those are the only that come to mind! Source(s): Pharmacy student
http://video.google.com/videosearch?q=fi…
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