Anyone think through anatomy?

1. Systemic lupus erythematous (often simply called lupus) is a condition that sometimes affects young women. It is a chronic (persistent) inflammation that affects all or most of the connective tissue proper contained by the body. Suzy is told by her doctor that she has lupus, and she asks if it will have widespread or merely localized effects inside the body. What should her physician answer?

2. Mrs. Lindsey sees her gynecologist because she is unable to become pregnant. The doctor discovers granulation tissue in her vaginal strait and explains that sperm are susceptible to some of the same chemicals as bacteria. What is inhibiting the sperm?

Please help!!
Answers:
1 - systemic resources it affects the whole body. the effects will be widespread (muscoloskeletal, cardiac, dermathologic, hemathologic...)

2- it probably is an actinomycosis, but i do not know what molecule exactly is inhibiting the sperm

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